Ghulmiyyah L, Nassar A,Usta I. Intravenous oxytocin use to decrease blood loss during cesarean section. What is the optimal dose: A randomized blinded trial.
The aim of this study is to determine the optimal dose of intravenous oxytocin to decrease the amount of blood loss during cesarean section.

Nassar A, Musallam K, Succar J, Usta I. Fasting during Ramadan: is it a risk factor for preterm labor and delivery? This study aims to determine the effect of fasting during the month of Ramadan on preterm labor and birth. In addition, it will study the difference in the effect at different gestational ages as compared to non-fasting pregnant women matched for both maternal and gestational ages, as well as parity and body mass index. The study hypothesis is that even short periods of dehydration and food deprivation in those patients increase their risk of having preterm labor and delivery. The data generated will be used to better counsel patients who plan to fast during the month of Ramadan regarding the risks of this practice.

Nassar AH, Berjawi G, Ghulmiyyah L, Usta I. Aromatase Inhibitors for the Medical Management of Uterine Leiomyomas in Perimenopausal Women: A pilot Study. The objective of our study is to assess the effect of aromatase inhibitors on the size of leimyomata in perimenopausal women. The null hypothesis is that aromatase inhibitors result in a clinically significant rduction in the size of fibroids that could obviate the need of surgical intervention in this group of patients.

Nassar AH, Hannoun A, Chaaban S, Elias E, Usta IM. The effect of the subspecialty on the acceptance of prenatal diagnostic tests is low
risk pregnant women. This study aims at determining the effect of he subspecialty of the obstetrician on the acceptance of women to undertake
tests like triple screen and amniocentesis.

Nassar AH, Abdel Reda H, Succar J, Sayegh L, Usta I. Gestational age at elective induction of labor in relation to the neonatal outcomes. This is a
prospective study that aims at evaluating the neonatal outcomes of infants born after elective induction of labor in relation to the gestational age.

Nassar AH, Khalife T, Awwad J, Saasouh W, Hayek S, Najjar Y, Usta IM. The incidence of gestational diabetes mellitus (GDM) in twin pregnancies
receiving prophylactic 17alpha-hydroxyprogesterone caproate. The objective of this study is to check if the added progesterone burden of 17alpha-hydroxyprogesterone caproate would further worsen the diabetogenic milieu of a twin pregnancy that is already at a higher risk of GDM.

Nassar AH, Succar J, Musallam K, Usta I. Fasting during Ramadan: is it a risk factor for preterm labor and delivery? This study aims to
determine the effect of fasting during the month of Ramadan on preterm labor and birth. In addition, we will study the difference in the effect at
different gestational ages as compared to non-fasting pregnant women matched for both maternal and gestational ages, as well as parity and body mass
index.

Hannoun A, Chaaban S, Elias E, Usta IM, Nassar AH. Does parity independently affect the acceptance rate of undergoing prenatal diagnosis?. This study
aims at studying the effect of parity on the acceptance of low risk women to perform tests like triple screen and amniocentesis.

Nassar AH, Murad M, Abdallah R, Usta IM. Progesterone to reduce recurrence of preterm delivery: are we following the evidence? The study aims at
studying whether obstetricians are implementing the recommendations endorsed by the American College of Obstetricians and Gynecologists regarding the
importance of giving progesterone supplementation to women who have previosuly delievered prior to 37 completed weeks of gestation.

Nassar AH, Johnny Awwad, Ghazeeri G, Charara I, Usta IM. Prevention of preterm delivery in twin pregnancies by 17 alpha-hydroxyprogesterone caproate. This is a randomized double blinded trial that aims at comparing the effectiveness of 17 alpha-hydroxyprogesterone caproate, a natural metabolite of progesterone, in preventing delivery at less than 37 weeks of gestation in a population of 290 patients with twin gestations between 16 and 20 weeks of gestation compared to a placebo.

Nassar AH, Usta IM, Awwad J, Seoud M, Mroueh A. A randomized trial of two regimens of misoprostol for second trimester termination for intrauterine fetal death. This study aims at comparing the efficacy, safety and patient satisfaction with misoprostol given vaginally (the current standard) to that given sublingually.

Nassar AH, Mehio G, Usta IM. Amniocentesis complications in relation to gestational age. This is a case-control study where all patients undergoing amniocentesis are prospectively followed up during pregnancy to determine their obstetrical outcome and any complications that might be attributable to amniocentesis. They will be compared to patients of similar gestational and maternal age who did not undergo the procedure.

Usta IM, Hobeika EM, Nassar AH. Complications following fetal reduction from higher order pregnancies to twin gestation. This is a prospective study aiming at determining the complications following fetal reduction from higher order pregnancies (triplets, quadruplets, etc….) to twins. The complications will be compared to those occurring in IVF twin gestations.

Nassar AH, Zoorob D, Salam O, Usta I. Pregnancy complications in pregnant women with antenatally diagnosed fibroids. This study aims at comparing the maternal complications in patients diagnosed with leiomyomata during pregnancy versus those without myomas.

Ihab Usta, Anwar Nassar. The utility of the triple screen as a screening test for aneuploidy in the Lebanese population. The objective is to determine the acceptance rate for performing second trimester screening for aneuploidy in Lebanese pregnant women.

Muhieddine Seoud co investigator with Dr Hala Tamim, Dr Faysal El-kak. Study on the use of folic acid in pregnancy in Lebanon.

Muhieddine Seoud as principle investigator and co-investogators: Dr Fadi geara, Dr Ali Shamsseddine, Dr Ali Khalil. The study of Cisplatin Vs Taxol as concurrent chemotherapy for the treatment of advanced cervical cancer. 2002-present.

Muhieddine Seoud as principle investigator, and co-investigators: Dr Adnan Mroueh, Pierre Zalloua, Hanna Kaspar, Rima Ballout, Ali Khalil, Fadi Geara. The study of HPV in Cervical and vulvar cancer. 2001-present.

Muhieddine Seoud as regional investigator and principle investigators outside Lebanon. Prospective randomized multinational study of CPT 11 in advanced cervical cancer. Study in progress. 1999-present.

Muhieddine Seoud as principle investigator and co investigator with Dr Ali Shamseddine and Nagi El-Saghir. Review of clinical characteristics of Breast cancer cases treated at AUBMC.

Muhieddine Seoud as principle invertigator, and co investigator with Dr Ali Shamseddine and the Lebanese cancerepidemiology group. The study of the cancer incidence in Lebanon 1993 and 1998.

Muhieddine Seoud as principle investigator,and co investigator with Dr Ali Shamseddine. A multi center study of second line Intravenous Topotecan in advanced epithelial ovarian cancer. June 1997.

Antoine Abu Musa, Antoine Hannoun, Ihab Usta, Nabil Khoury, Muhieddine Seoud, Laila Zahed, Anwar Nassar. Type and frequency of chromosomal aberrations in couples with primary infertility. The objective of this study is to evaluate the type and frequency of chromosomal abnormalities among infertile couples and to compare it to fertile couples. The results of this study might be relevant to the design of appropriate diagnostic strategies for the future.

Ali Khalil, Muhieddine Seoud. Vulvar cancer in Lebanon: review of 92 patients; 1958-1994.

Muhieddine Seoud as principle investigator and Ali Khalil. Survey of the nutritional status and the need for nutritional supplementation of a representative segment of the Lebanese population.1994.

Muhieddine Seoud as principle investigator, and co-investigators, Ali Khalil, Georges Araj. The study of the microbiology and response to systemic and local therapy of vulvovaginal candidiasis, September 1994.

Muhieddine Seoud as principle investigator, and Ali Khalil. Mass screening for tuberculosis in the obstetrical population at AUBMC. Jan 1994.

Muhieddine Seoud as principle investigator, and co-investigators: Ali Khalil, Ali Shamsseddine, Ziad Salem, Nagi Saghir, Kamal Bikahzi, Hanna Kaspar, Fadi Geara. Tamoxifen and endometrial and pelvic pathologies in patients with breast cancer, a prospective study. November 1993-2001.