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- A new Server running the recent Linux versions of Insight II and GCG Wisconsin Package is installed.

- DMol3 and Gaussian software for quantum mechanical calculations are available, interfaced with Cerius 2 modeling software.

- The PDB (Protein Data Bank) database from RCSB (Research Center for Structural Bionformatics) is available locally at the CSBL. Users can automatically retrieve protein structure files and perform computational analysis including:

  • Structure refinement
  • Homology modeling
  • Energy minimizations
  • Dynamics simulations
  • Solvent simulations
  • Protein-ligand binding affinity
  • Ligand docking
  • De novo ligand construction
  • Proteolytic enzyme analysis
  • Phylogenetic studies